The rising prevalence of opioid-related health harms (OHH) Indicates a need to understand the end-of-life needs of people with OHH. Opioid use is associated with increased risks of life-limiting conditions. People with a history of OHH face barriers accessing palliative care including opioids for symptom management. We will explore palliative care, opioid prescribing, and end-of-life outcomes in Ontario.
We will use mixed-methods; Phase 1 will use administrative data to identify differences in palliative care provision, prescribing, and outcomes between people with and without OHH to evaluate relationship between receipt of palliative care with opioid prescribing and outcomes. In Phase 2, we will interview people with OHH, caregivers, and care providers to explore experiences and stigma surrounding palliative care for people with OHH.
Using innovative knowledge translation activities (e.g., art installation, video series), we will impart knowledge, inform research, and generate awareness about people with OHH at the end of life.
Recruitment to platform at one of the hubs
Consent and enrolment in platform
Collection of key data, minimizing participant burden for individual trials
Screening automatically for all trials taking place on the platform, maximizing options for patients and caregivers
Trials – patients and caregivers participate in trials they are eligible for
Ongoing check-ins – patients and caregivers are followed until they choose to stop participating or until patient death
Bereavement – we follow caregivers for up to three years and offer them bereavement interventions
By linking practice and research, the platform will improve care for patients and families affected by advanced cancer.
Practice
Clinicians, patients, and caregivers identify areas for improvement in care.
PCPCRC
Supports foundational research that identifies promising interventions.
Research Platform
Comprised of Phase 3 RCTs, Research Hubs, Data Strategy.
Evaluation of hub model and data strategy to optimize research.
Training and mentorship underlie and uphold all activities in the cycle.